Line Plot from Scientific Research

Figure shows the predicted mean NMR-derived metabolic trait trajectories from age 7–26 years for ALSPAC offspring born large for gestational age (LGA, N =500) and appropriate size for gestational age (AGA, N =4480), for 18 metabolic traits that were identified in the meta-analysis. Predicted values were obtained from adjusted (for sex and confounders) natural cubic spline mixed effects models that included an interaction term with age to allow LGA and AGA groups to have different mean metabolic trait trajectories. Predicted mean differences are presented in Figure S2

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