Box Plot from Scientific Research

Comparisons of serum metabolites related to arginine and proline metabolism, arachidonic acid metabolism, ubiquinone and other terpenoid-quinone biosynthesis, and glutathione metabolism showed significant elevation or depletion stratified by the severity of chronic kidney disease (CKD). Statistical analysis was performed by Wilcoxon rank-sum test (* P < 0.05, ** P < 0.01, *** P < 0.001). BenjaminiHochberg procedure was employed for the multiple test adjustments. GSH metabolism, glutathione metabolism; AA metabolism, Arachidonic acid metabolism; Ubi biosynthesis, ubiquinone and other terpenoid-quinone biosynthesis; mod-CKD, moderate CKD; ESRD, end-stage renal disease; LTB4, leukotriene B4; TXB2, thromboxane B2; 12-KETE, 12-keto-5,8,10,14-eicosatetraenoic acid

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