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Summary of the study design. GWAS, genome-wide association study; EAS, East Asian population; EUR, European population; PRS, polygenic risk score; AUC, area under the receiver operating characteristics curve; PLCO, Prostate, Lung, Colorectal and Ovarian cancer screening trial; GECCO, Genetics and Epidemiology of Colorectal Cancer Consortium; CORSA, Colorectal Cancer Study of Austria; BBJ, BioBank Japan Project

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