Bubble Plot from Scientific Research

Summary of GO molecular function enrichments across all time points with false discovery rate (FDR) < 0.05. REVIGO in conjunction with a custom python script was used to generate the plot [ 33 ]. The axes are derived from multidimensional scaling and measure semantic similarity, enabling the removal of redundant GO terms and visualization of the similarity between GO categories. Each circle represents a GO term and circles near each other contain similar genes in the corresponding gene set. Labeled gene sets are generally those with the lowest FDR in a cluster of terms on the plot or those highlighted in the text. The size of the circles indicates the number of genes that are driving the enrichment for that category.

DOI