Line Plot from Scientific Research

Schematic diagram of the integrative analysis of RNA-seq and differential binding of HA-CTCF-ZF mutants ChIP-seq. For each gene, initially, we considered all the peaks within [TSS - 50 kb, TES + 50 kb]. The RNA-seq and ChIP-seq fold changes were converted to z -score, then multiplied together for each gene-peak pair to get a combined score. Pareto optimization was performed to determine the most correlated peak-gene pairs.

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