Line Plot from Scientific Research

Biolayer interferometry (BLI) traces assessing binding of Fabs isolated from TM4-Core−GC cells isolated from C56BL/6J mice on day 13 after HIV antibody injection. Colored curves show Fabs with binding profiles higher than polyreactive ED38 control Fab and gray curves represent Fabs with affinities similar or lower than ED38. Left graph: biosensor chips were loaded with TM4-Core immersed in solutions containing Fabs. Curves in red represent Fabs binding better than controls. Numbers show the number of red and gray curves. Right graph: GC Fabs were immobilized on biosensor chips and immersed in solutions containing TM4-Core trimer. Curves in green represent Fabs binding better than controls. Numbers of green and gray curves for each respective experimental condition are shown.

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