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Schematic diagram showing the experimental design and procedure of AEBP1 overexpression. AdV-Vector-Vehicle: fibroblasts transfected with adenovirus harboring empty vector and no TGF treatment was performed; AdV- AEBP1 -Vehicle: fibroblasts transfected with adenovirus harboring AEBP1 cDNA and no TGF treatment was performed; AdV-Vector - TGF: fibroblasts transfected with adenovirus harboring empty vector and followed by TGF treatment; AdV- AEBP1- TGF: fibroblasts transfected with adenovirus harboring AEBP1 cDNA and followed by TGF treatment. Three independent experiments were performed for each group. Normal human ventricular cardiac fibroblasts (passages 5-6) were used.

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