Chiclet plot displaying the differential HDX (ΔHDX) plots for (AcrASMgCl2pH 6.0) - (AcrASMgCl2pH 7.4). Blue signifies areas with decreased HDX between states, red signifies areas with increased HDX between states and white signifies areas with no significant change in HDX. Significance was defined to be ≥0.5 Da change with apvalue ≤0.01 in a Welch’s t test (n= 4). Boundaries of peptides within areas of significant changes are shown (left, y-axis) and AcrA features are labeled (right, y-axis).
