Bubble Plot from Scientific Research

pTMB counteracts the negative impact of aneuploidy on cytolytic activity and response to ICB (GZMB, IFNG, PRF1: beta pTMB = 0.5, P < 3 x 10 -3 ; beta aneuploidy in [-0.09, -0.03], P > 0.05; ICB response, beta pTMB = 1.8, P = 4.0 x 10 -3 ; beta aneuploidy = -0.56, P = 0.21; beta : logistic regression model coefficient, two-sided P values are calculated assuming normally distributed test statistic).

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