The background rate of genomic loss was quantified in 31 tumor types from TCGA (N = 5,244). In all tumor types, the rate of loss was significantly higher in diploid (allele-specific copy numbers 1–1) versus haploid (single-copy; allele-specific copy numbers 1–0) regions of the genome (two-sided Mann–Whitney U -test, P < 0.05 for all tumor types except for UCS for which Mann–Whitney P = 0.067), supporting the notion that mutations that reside in haploid regions of the genome would less likely be lost. Box plots depict the median value and hinges correspond to the first and third quartiles. The whiskers extend from the corresponding hinge to the furthest value within 1.5 x interquartile range from the hinge.
