Volcano Plot from Scientific Research

Volcano plot analysis. Each point represents a ChIP-seq experiment and is highlighted as red for cardiovascular cells, green for induced pluripotent stem cell-derived cardiac cells, blue for muscle cells and gray for other cell types. P values were calculated with two-tailed Fisher’s exact probability test. The x axis shows log 2 -transformed fold enrichment of transcription factor in 150 AF-associated loci, compared to 150 randomly selected genomic regions. The y -axis shows log 10 -transformed P value for enrichment. The dashed line indicates the significance threshold level of P = 0.05, and the dotted line indicates P = 0.05/15,109.

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