Scatter Plot from Scientific Research

Maximum cytotoxic activities of CD123-IgG1 + and CD123-NKCE molecules against blasts from patients with AML. Blast cells from seven patients with AML were used as targets and purified NK cells from ten healthy donors were used as effectors. Delta (Δ) maximum lysis, defined as percentage maximum lysis of the compound minus percentage background lysis of the isotype control molecule (IC-IgG1 + or IC-NKCE), were monitored from the dose response of each compound, and plotted separately for all couples of primary CD64-positive and CD64-negative AML sample/NK donor. (* P ≤ 0.05; ** P ≤ 0.005; two-sided Wilcoxon matched-pairs signed rank test).

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