Table Image from Scientific Research

Substitutions incorporated into selected TadAs from structure-guided screen round 1 (CABE-T3 editors; TADAC-3 deaminases) and round 2 (CBE-T1 editors; TADC-1 deaminases). Substitutions incorporated in TadA*8.20 relative to WT TadA are highlighted in gray, and those identified in directed evolution campaigns 1 and 2 are highlighted in violet and orange, respectively. Values in the last column represent the number of substitutions added to each variant compared to WT TadA.

DOI