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Graph represents the length of HIOs from control (black circle) or humanized (red square) group at 12 weeks ( n = 6 control and 7 humanized mice), 16 weeks ( n = 9 control and 9 humanized mice) and 20 weeks ( n = 4 control and 3 humanized mice) post-transplantation. Mean ± s.d. Multiple Mann–Whitney tests (two-sided); P = 0.1666 for 12 weeks, P = 0.7120 for 16 weeks and P = 0.714 for 20 weeks. NS, not significant. Graph representative of at least three independent experiments.
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