Left: an example of segmented centrosome and matrix. The PCM consists of an interconnected fibrous mesh, surrounding centrioles composed of 13 protofilament microtubules. This PCM is capable of nucleating 11 protofilament microtubules by permitting access of client molecules through pores in the material (right: a 2D slice of the interconnected mesh) large enough to accommodate the client proteins SPD-2, PLK-1, Aurora A kinase (AIR-1), and tubulin dimers.