Bar Plot from Scientific Research

Prime editing of genomic DNA in HEK293T cells by the MS2-P65-recruiting PE3 and PE5 systems. The editing efficiencies reflect the sequencing reads that contained the intended edits and did not contain indels among all treated cells, with no sorting. The gray bar indicates the indel frequency coupled with the editing efficiency indicated by the left closest bar. Bars represent the mean of n = 3 independent replicates. The error bars in all figures represent the SDs. The P values were calculated by a two-tailed t test. ** P < 0.01; * P < 0.05.

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