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Serum levels of liver enzymes, alanine aminotransferase (ALT) and aspartate aminotransferase (AST), renal parameters, blood urea nitrogen (BUN), and creatinine 24 h after intravenous administration with PBS, C-CholF3 and C12-200 LNPs at a dose of 0.5 mg kg-1(n= 3, SD,*p< 0.05,**p< 0.01,***p< 0.001,****p< 0.0001; NS, not significant, one-way ANOVA with Bonferroni post hoc analysis).

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