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Levels of IL-6, IL-1, and TNF in mice intravenously treated with C-CholF3 and C12-200 LNPs at a dose of 0.5 mg kg-1(n= 3 biologically independent mice, SD,*p< 0.05,**p< 0.01,***p< 0.001; NS indicates no significance, one-way ANOVA with Bonferroni post-hoc analysis). PBS-injected mice were kept as the control group.
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