The S. Tm load, expressed in CFU per gram of feces, at 96 h p.i., is plotted (y axis) and compared between S. Tm mono-infected and S. Tm + E. coli 8178 infected mice. The S. Tm and E. coli 8178 mutant strains tested are listed. The x axis represents the time p.i. (in h). Dotted line, limit of detection; p-iroN, plasmid encoding the iroN gene. (A–D) Bars, median. Two-tailed Mann-Whitney U tests to compare two groups in each panel. p≥ 0.05 not significant (ns), p< 0.05 (*), p< 0.01 (**), and p< 0.005 (***).