STABLE compared with unpaired image-to-image translation methods in the calcium imaging translation task, converting cytosolic GCaMP to nuclear-localized GCaMP. From left to right: STABLE, CycleGAN, MUNIT, SANTA, and UTOM. Input cytosolic GCaMP (cyan) is overlaid with the translated nuclear-localized GCaMP (red). Magnified views of the boxed regions are presented along the bottom. Scale bar for large views, 10 m. Scale bar for magnified views, 5 m.