KaplanMeier graph showing the proportion of patients without a diagnosis of dysplasia for each risk group over time with the p value for the generalised Wilcoxon test reported. All patients with Barrett's oesophagus were risk stratified according to both their clinical risk factors and capsule-sponge biomarker results. Patients with Barrett's oesophagus who were biomarker positive on the capsule sponge were further stratified into high risk tier 1 if they had both glandular atypia and aberrant p53. All other Barrett's oesophagus patients who were biomarker positive on the capsule sponge were classified as high risk tier 2. For some patients, histopathology results for more than one follow-up endoscopy post-capsule sponge were obtained. For these cases, the first endoscopy with a diagnosis of dysplasia was included in this graph.
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