Line Plot from Scientific Research

Optogenetic stimulation of CA3→CA1 inputs activated 64.5% of pyramidal layer interneurons (PyrInt; 40 of 62) and 34.8% of rad interneurons (23 of 66), but no l-m cells (0 of 18). EC→CA1 input stimulation recruited 42.3% of l-m cells (11 of 26), with minimal activation of PyrInt (2 of 46) and no rad neuron responses (0 of 63). Significant responses were defined as firing rates exceeding the baseline mean by 2 standard deviations and independently confirmed with ap< 0.01 threshold in a permutation test.

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