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Survival curves of MED1712FH and MED113FH PDX-bearing mice receiving Vehicle- or IDA after tumor bioluminescence signals reached threshold (n≥ 9 mice per group). Data shown as mean ± SD. (E). Number of mice and median survival for each group indicated in (F). Statistical significance calculated by two-sided t test (E) or Log rank Mantel-Cox test (F).*p< 0.01,**p< 0.001, n.s.p> 0.05. See also Figure S6 and Table S6.

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