Boxplot of somatic tumor SNV mutation frequencies. (n= 3 Elp1WT;Ptch1gRNA vs. n= 7 Elp1HET;Ptch1gRNA tumors). Data shown as mean ± SD (D), mean ± SEM (G), or boxes = median, first and third quartiles, whiskers = 1.5x IQR (I). Statistical significance determined by Log rank Mantel-Cox test (B), two-sided ttest (D and G), or Mann-Whitney test (i).∗p< 0.05,∗∗p< 0.01, n.s.p> 0.05. See also Figure S4 and Table S3.
