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Npy, Darpp32, and Gpr83 immunofluorescence intensity within Darpp32 intensity normalized to DAPI volume are significantly down in 12-week R6/2 compared with NT (n= 3/genotype). Scale bar, 3 μm. Summary data are represented as mean ± SEM with individual points representing each sample. Statistical significance was assessed using two-tailed unpaired Student’s t test, ns: p > 0.05.
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