Workflow from Scientific Research

Open access visualization of Workflow, Line Plot, Neural Circuitry, Intestinal D-glucose Sensing, CRFPVN neuronal activity
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Proposed working model illustrating the neural circuitry linking intestinal D-glucose sensing to CRFPVNneuronal activity. During fasting, ID D-glucose infusion selectively suppresses this activity via a spinal nerve-mediated pathway that inhibits fasting-sensitive PBNdl neurons. By contrast, other nutrients (e.g., L-glucose and lipids) activate CRF⁺PVN neurons via vagal and/or spinal pathways, independently of fasting-sensitive PBNdl neurons. See alsoVideo S1.

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