Microscopy from Scientific Research

Hdac9CREApoemice receiving Western-type diet for 8 weeks were treated with the NLRP3 inhibitor MCC950 (10 mg/kg) three times a week in parallel to the diet feeding. ControlHdac9ApoeandHdac9CREApoemice were also placed on a Western-type diet for 8 weeks and received PBS as vehicle control. (N) Representative Picro-Sirius red-stained aortic root plaques (indicated by arrowheads). Scale bars = 200 m.

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