Line plots showing average log2fold change in chromatin occupancy of CBX2, CBX4, CBX8, PCGF4, and PCGF2 at PRC1/2 target genes between SU-DIPGXIII-H3K27M and H3K27M-KO cells (left, middle). Line plot showing average log2fold change in RNA abundance of PRC1/2 target genes between SU-DIPGXIII-H3K27M and H3K27M-KO cells (right). Genes are separated into quartiles based on H3K27me3 levels in SU-DIPGXIII-H3K27M cells (n= 3 biological replicates).
