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Results of a cold tolerance test in control and Pla2g15 KD mice kept at RT or in the cold for 6 h, where core body temperature was recorded hourly (n= 6 biological replicates/group). A two-way ANOVA with interaction was used to assess the effect of Pla2g15 KD and environmental temperature on core body temperature. Significant differences (p< 0.05) in core temperature due to environmental temperature of mice within the same group (Pla2g15 KD or controls) are indicated by asterisks (*). Significant differences in core temperature between the control and KD mice in the cold (4°C) are indicated by a pound sign (#).
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