Bars (one per animal) indicate the range of CAG repeats between the modal CAG length (black line at the bottom of each bar) to the right CAG peak boundary at 10% of peak height (top of each bar). Threshold 1a (lowest dotted line) represents the mean of Mod-CAG lengths in Q140/Msh3-hom at 6 months and 20 months, threshold 1b represents the mean of the upper CAG lengths in Q140/Msh3-het at 6 months and Q140/Msh3-hom at 6 months and 20 months, and threshold 2 represents the mean of the upper CAG lengths in the NIs only group, i.e., Q140 at 6 months, Q140/Msh3-het at 12, 16, and 20 months, and Q140/Pms1-hom at 12 months.
