Gel from Scientific Research

Cross-linking assays of SERCA2b with C4orf3/ALNW48Cin isolated microsomes at indicated SERCA2 catalytic states. The cross-linker BMH was added to induce the SERCA2-C4ORF3 complex formation. The assays were performed in three independent biological samples. Bottom: catalytic cycle of SERCA to transport Ca2+into the ER lumen. Indicated compounds were used to induce the specific catalytic states of SERCA.

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