(Left) Representative IMF images of the GCN2i experiment. (Right) Quantifications of re-epithelialization. Each data point denotes one mouse. Solid lines denote the median, and dashed lines denote the 75th and 25th quartiles. Significance was determined by Student's unpaired t test. Red arrows note a lack of re-epithelialization in GCN2i-treated mice compared with VEH-treated mice (yellow arrows). Skin epithelium is demarcated by white dotted lines. The scab-neo-epidermal interface is traced in yellow dashed lines. Scale bar, 50 um. Error bars are mean SEM. * denotes a p value of < 0.01,* denotes a p value of < 0.05, and ns denotes a p value of > 0.05. Please see Figure S5 for more details.
