Bar Plot from Scientific Research

(Top left) Experimental design to assess the effects of pharmacological elevation of the ISR during wounding. (Top right) Quantifications of re-epithelialization. Each data point denotes one mouse. Significance was determined by two-way ANOVA with Šídák's multiple comparisons test. VEH, vehicle; SALU, salubrinal. (Bottom) Representative IMF images. Red arrows note a lack of re-epithelialization in WT VEH compared with all other conditions (yellow arrows). Skin epithelium is demarcated by white dotted lines. The scab-neo-epidermal interface is traced in yellow dashed lines. Scale bar, 50 μm. ∗∗∗∗denotes a p value of < 0.0001,∗∗∗denotes a p value of < 0.001,∗∗denotes a p value of < 0.01,∗denotes a p value of < 0.05, and ns denotes a p value of > 0.05. Error bars are mean ± SEM.

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