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A model illustrating homeostasis of brain phosphoproteome linking sleep regulation and functions. Data are mean ± s.d. Two-way ANOVA with Sidak’s test ( b , c ); one-way ANOVA with Tukey’s test ( i , j ); log-rank (Mantel-Cox) test ( o , q ); two-tailed unpaired t -test ( l ). * P < 0.05; † P < 0.01; ‡ P < 0.001; NS, not significant, P > 0.05. n refers to the number of biological replicates.

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