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The turnover of M 1 L as inferred from fluorescence data, in experiments with 100 nM M 1 L , 100 nM N 3 and variable concentrations of the template [{T}_{13}]_{0} (6t/8h). A large proportion of M 1 L is observed to react, even for a concentration of [{T}_{13}]_{0} 400 times lower than the number of monomers, reaching turnovers above 20 products per template. The template-free leak reactions are essentially negligible (0.32 0.06 M -1 s -1 ) even compared with the lowest template concentration regimes.
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