Distribution of tumor markers stratified by haplogroup and ICI response for IFNg score ( n = 166), log-transformed TMB ( n = 376), percentage tumor infiltration by CD8 + T cells ( n = 182) and PD-L1 status ( n = 476). Box plots depict lower and upper hinges (25th to 75th percentiles), median value (central line), whiskers extending from the hinges (largest and smallest values no more than 1.5 times the interquartile range) and outlying points outside this range (solid points beyond the whiskers). P values derived from Kruskal-Wallis tests.
