Forest plot from logistic regression analysis showing the ORs, log odds, CIs and two-tailed P values when comparing NIVO treatment outcomes for HG-T versus other MT-HGs. Black boxes represent the point estimate for the main effect size (log odds) in discovery and validation cohorts and the lines extending from them represent the 95% CIs. Diamonds represent the log odds point estimate for pooled analyses estimating the overall magnitude of effect. Point estimates to the left of the dashed line indicate increased odds of NIVO CB, while point estimates to the right indicate increased odds of no NIVO CB. CIs that do not cross the dashed line indicate a statistically significant point estimate (P < 0.05).