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Phylogenetic tree depicting MT-HG lineages and CM-067 NIVO discovery cohort treatment efficacy (n = 115 patients) with CB/NCB frequencies (counts) for the major European haplogroups (H, U/K, T, J, V, I, X, W). Inset shows CB/NCB proportions within each major European haplogroup (H, J, T, U/K). Dark bars represent participants with NIVO CB (CR, PR or dSD). Light bars represent participants with NIVO NCB (pSD or PoD).

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