Forest Plot from Scientific Research

Comparison of the estimates (HR and 95% CI) of the RCT and their emulation in FinnGen. Points represent estimated HRs; horizontal lines denote 95% CI. The vertical continuous line indicates the null value (HR = 1). Empareg, BI 10773 (Empagliflozin) cardiovascular outcome event trial in patients with T2D mellitus ( n RCT = 7,020, n Emulation = 4,522); Tecos, sitagliptin cardiovascular outcomes study (MK-0431-082; n RCT = 14,514, n Emulation = 1,094); Aristotle, apixaban for the prevention of stroke in patients with AF ( n RCT = 18,240, n Emulation = 2,292); Rocket, an efficacy and safety study of rivaroxaban with warfarin for the prevention of stroke and noncentral nervous system systemic embolism in patients with nonvalvular AF ( n RCT = 13,916, n Emulation = 1,030).

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