Ranking of hubs quantified by weighted degree (strength) of the pairwise statistic matrices. Absolute values are taken from the pairwise statistics before ranking. Note that pairwise statistics with positive correlations with spatial distance (shown in c ) have flipped rankings to ensure a more consistent hub representation. Regions are ordered by intrinsic functional networks from ref. 15 for left and right hemispheres. Darker red means greater weighted degree (‘hubness’). VIS, visual; SM, somatomotor; DA, dorsal attention; VA, ventral attention; LIM, limbic; FP, frontoparietal; DMN, default mode network. The organization of hubs when considering positive and negative values separately can be found in Supplementary Fig. 2 . The similarity of hub organization across pairwise statistics and their representation on the cortex are shown in Supplementary Fig. 3 .