Proportions of pTau + and intraAβ + cells in each neuronal subtype cluster separately for CtrlCV (sections from n = 6 brains), CtrlTREM2 ( n = 6), AlzCV ( n = 18) and AlzTREM2 ( n = 13) samples. Quantification was performed on three ROIs acquired from a single section of each sample and pooled together. Coloured boxes on the left highlight groups of neuronal types (excitatory, inhibitory and unclassified neurons) to which clusters were assigned to (assigned neuronal type).