IMC images showing co-localisations of: RORB + and AT8 + pTau in a AlzCV (Braak 5/6) tissue section. Double-positive neurons (RORB + AT8 + in b ; RORB + 4G8 + in d ; GAD1 + 4G8 + in e ; yellow arrowheads) are found in the cortical layers shown in Fig. 3 b, d, f. Source data are provided as a Source Data file. Scale bars in (b,d,e) represent 100 μm.