Time-resolved ORA depicting the significance of the reconstructed networks highlighting enrichment on the GO term ossification (GO:0001503). Each point corresponds to a gene set captured by each network or DEGs (in the y-axis), and the x-axis shows the gene ratio. The color intensity indicates the Adj. p -value from Fishers Exact Test, with a gradient color map ranging from low (light) to high (dark) significance, as normalized by the color bar at the bottom. Point size represents the number of genes that represent the GO term, while gene ratio represents the fraction of identified GO-term-related genes over the total number of known GO-term-related genes. Networks at each time point are arranged in a grid, allowing for a comparative view of regulatory changes over time. Only significant interactions (FDR-BH-corrected p -value < 0.01 ) are represented
