Illustration from Scientific Research

Schematic of how the correlation between tissue would identify the source of bacterial metabolites. ({rho}_{Dec_GI}) denotes the correlation of metabolite abundance in between decidua and GI tissues, and ({rho}_{Mec_GI}) denotes the correlation of metabolite abundance between meconium and GI tissues. Maternal microbiota-derived metabolites that cross as metabolites are expected to have ({rho}_{Dec_GI}) >> ({rho}_{Mec_GI}), while metabolites that are potentially locally produced by fetal microbiota within the GI track are expected to have ({rho}_{Dec_GI}) << ({rho}_{Mec_GI}).

DOI