Top panel, mean sequencing coverage in each microdissection. Donors (M, male; F, female) are ordered by disease and age. The number of SNVs and indels detected per microdissection within the coding exome across WGS ( n = 77) and WES ( n = 229) data (for five samples for which dual WGS and WES were performed, only WGS calls are shown). Variants are colored by type.