Line Plot from Scientific Research

Upper panels each show 4 Mb of published strand-specific population-level Okazaki fragment sequencing depth and the determined Ok-seq initiation (dark blue) and termination zones (light blue) [ 16 ]. Lower, zoomed in panels show ultra-long single-molecule nanopore sequence reads with DNAscent BrdU probabilities (black dots) and fractions BrdU incorporated (blue lines). As in Fig. 2 B, above each read are shown DNAscent replication forks with direction (arrows), initiation (light green bars), and termination sites (dark green bars). Example read showing two DNAscent initiation sites corresponding with published Ok-seq initiation zones.

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