Bar Plot from Scientific Research

Mutational profile of substitution signature SBS16 using the conventional 96 mutation type classification (top panel). Exemplar transcriptional strand asymmetry analysis for substitution signature SBS16 (bottom left panel). Exemplar genic versus intergenic regions analyses for substitution signature SBS16 (bottom right panel). X-axes in the bottom panels display six substitution subtypes based on the mutated pyrimidine base: C > A, C > G, C > T, T > A, T > C, and T > G, and the y-axes represent the number of mutations both for real and simulated mutations on transcribed and un-transcribed strands or genetic and intergenic regions. Simulated mutations are shown in shaded bar plots.

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