Bar Plot from Scientific Research

Indel frequencies of LAC12aGE-mediated genome editing activities toward the DNMT1 gene in HEK293T, U87MG, H460, and HeLa cells. Neg., negative control, transfected with Cas12a plasmid in the absence of crRNADNMT1. Pos., positive control, transfected with Cas12a plasmid and wt-crRNADNMT1. -UV, cells transfected with Cas12a plasmid/OFF-crRNADNMT1 in the absence of UV light. +UV, cells transfected with Cas12a plasmid/OFF-crRNADNMT1 in the presence of UV light. Data are presented as mean SD (n= 3). The original gel electrophoresis experiments corresponding to the indel calculations are presented in Figures S12S14.

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