The correlation between the rate of visual field progression and serum homocysteine levels was calculated in a secondary analysis of the UKGTS using linear mixed models. There were no significant associations of serum homocysteine levels to mean deviation (MD) rate, pointwise sensitivity for all locations (pointwise linear regression, PLR), and the PLR for the fastest 5 locations over time in the whole cohort or when split into placebo and treated groups. Other parameters are relevant to visual field effects as expected (all,n= 147 patients; placebo,n= 73; treatment,n= 74). Also seeFigure S1C.
