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Cos7 cells were incubated for 8 h or 20 h in serum-free media containing 25 μM, 50 μM, or 100 μM of the indicated compounds. 0.5% DMSO was used as control. Cytotoxicity was assessed based on the release of LDH into the cell culture supernatant; values were normalized to controls as determined upon treatment with 2% Triton X-100 in assay medium.

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